Ozempic: Weighing Risks and Benefits

Potentially Life-Changing Weight-Loss Medications: What to Consider

Hundreds of thousands of people worldwide are taking drugs like Ozempic to lose weight. But what do we actually know about them? This month, our experts explore their rise, impact, and potential consequences.

Potential Benefits

1. Weight Loss: The largest, well-conducted research study of semaglutide found that people who took the medication lost weight – significantly more than those who took a placebo (-14.9% of their body weight compared with -2.4% of body weight).

2. Reducing Chronic Disease Risk Factors: When people lose at least 5% of their body weight, physiological changes often occur, including lowered cholesterol levels, blood pressure, and blood glucose levels, which reduce the risk of chronic diseases.

3. Improving Quality of Life: People using semaglutide, such as Oprah Winfrey, report a reclaiming or turning point of their life, social situation, and body image.

What About the Risks?

1. Gastrointestinal Symptoms: In one clinical trial, nearly half (48.6%) of people taking semaglutide reported experiencing adverse effects, with nausea and vomiting being the most frequently reported.

2. Fatigue: Fatigue was the second most common side effect, affecting 6.3% of participants in another clinical trial.

3. Difficulty Accessing: Due to high demand, the TGA has warned significant Ozempic access barriers are likely to continue throughout 2024. Pharmacists are instructed to give preference to people with type 2 diabetes who are seeking the medication.

4. Concerns Over Marketing and Conflict of Interest: Some have raised concerns about the medication’s marketing, PR, and strong social media presence. Researchers may be influenced by their relationship with the manufacturer to produce study results that are more favourable to the medications.

Conclusion

Ozempic is a medication that should be used in conjunction with your health care provider. While it has shown promise in aiding weight loss, it is essential to consider the potential risks and benefits. Weight is only one aspect of your health and wellbeing; it’s crucial to prioritize eating well, moving more, and getting enough sleep.

FAQs

Q: Is Ozempic safe?
A: Australia’s Therapeutic Goods Administration (TGA) has approved Ozempic as safe to use, but it has not yet been approved for weight loss.

Q: What are the potential side effects of Ozempic?
A: The most common side effects include gastrointestinal symptoms, fatigue, and allergic reactions.

Q: How effective is Ozempic for weight loss?
A: Studies have shown that Ozempic can lead to significant weight loss, with an average weight loss of around 12.3kg over six months.

Q: Is Ozempic suitable for everyone?
A: Ozempic is not suitable for everyone, especially those with a history of pancreatitis, gastrointestinal disease, or severe kidney impairment. It is essential to consult your doctor before starting the medication.

Q: Are there alternatives to Ozempic for weight loss?
A: Yes, there are several other weight loss medications available, such as Wegovy and semaglutide. However, it is crucial to consult with your doctor to determine the best treatment plan for your individual needs.